Midway by means of his profession, Cees Dekker reinvented himself. Just after a long time of hardcore physics, he shifted his aim to ‘nanobiology’ with the turn in the millennium. A term he coined himself, as being a make a difference of reality.

You regularly get entangled in discussions about science and religion. You might have also prepared a number of textbooks on the subject. Don’t you are convinced at some time We're going to know anything and that God’s purpose will likely be around?

Multicolor imaging of your bacterial nucleoid and mobile division proteins with blue, orange, and around-infrared fluorescent proteins

Sculpting nano-electrodes using a transmission electron beam for electrical and geometrical characterization of nanoparticles.

This yielded a breakthrough. Within just a few months, we were capable to measure transportation by means of somebody solitary-walled carbon nanotube. Dependant on minimal-temperature experiments by a superb PhD college student in my team, Sander Tans (now a valued colleague and professor at Delft University of Know-how with the Lively study lab at AMOLF in Amsterdam), we confirmed that carbon nanotubes were being real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.

Electrical transportation in monolayers of phthalocyanine molecular wires and AFM imaging of just one wire bridging two electrodes

What distinguishes biology from chemistry is that these parts together make up a residing method. The key of stated lifetime, I think, lies from the interactions, the interplay of People molecules. The massive issue regarding the origin of life continues to be unanswered. How did we at any time evolve from easy molecules in the extremely intricate systems we see nowadays? We do not know. I want to work on These types of significant, open inquiries.’

Nanopores depict a chic and adaptable Device to measure single molecules. We analysis novel detection modes with sound-condition nanopores and also several solutions to evaluate proteins with nanopores. Assignments encompass the next:

2003, demonstrated the initial biosensors produced out of a carbon nanotube; fixed the composition and mechanism of DNA fix proteins; and discovery of a brand new method for fabricating solid-point out nanopores for DNA translocation

Extremely interesting, but that wasn’t truly wherever my interest lay. I wished to pioneer And that i experienced the feeling that was no more probable, because the most exciting essential insights had previously been uncovered. But my industry had created a lot of exciting new resources to measure particular person molecules. I made a decision that I desired to use this to biology, to take a look at it from the physical perspective.’

Tests pseudotopological and nontopological designs for SMC-pushed DNA loop extrusion versus roadblock-traversal experiments

Lots of new phenomena ended up found, and he and his research group established a number one position During this discipline of research. Dekker and his exploration group learned new physics of nanotubes along with explored the feasibility of molecular electronics. In 1998, they were being the primary to build a transistor based upon a single nanotube molecule.

2005, discovery in the system of DNA uncoiling by topoisomerase enzymes; discovery of extended-vary conformational adjustments in Mre11/DNA ceesdekker.net maintenance complexes; and very first drive measurements on a DNA molecule in a very nanopore

 Eventually, I'll briefly sketch many of our ideas to discover the creating of synthetic cells, especially our 1st techniques to determine artificial mobile division.